dp x dx > h / (2 pi) .
When you measure the position and momentum of a particle, you cannot measure the quantities with infinite precision. The product of the uncertainties must always be greater than some constant number (known as Planck's constant [denoted by h]) divided by 2 times pi. The uncomfortable notion is that the more precisely you measure the momentum, p, i.e., the smaller dp, in order to keep the product larger than some minimum value means that dx, the uncertainty in position, must be large (and vice versa). The upshot of this is that one cannot locate the position of a particle to infinite precision. One can only calculate the probability of where particles will be found.
Roughly for a particle of mass m, let's find this uncertainty (spread) in the location of the particle. A nice number to use for dp is to let the uncertainty in the momentum be given by m x c, so that
mc x dx greater than h ===> dx = Compton wavelength = W(Compton) ~ h / mc
You cannot localize a particle any better than roughly its Compton wavelength.
This breakdown occurs for masses known as the Planck mass which is defined as
Planck mass = M(P) = sqrt[hc/(2G)] ~ 5.5 x 10**(-5) grams
For reference purposes: m(proton) = 1.7 x 10**(-24) grams and m(electron) = 9.1 x 10**(-28) grams
The W(Compton) and R(Sch) which correspond to the Planck mass is
W(Compton) = h/mc = R(Sch) = 2GM/c**2 = 4 x 10**(-33) cm
This distance is known as the Planck length and the light travel time across this distance is known as the Planck time and is given by
Planck time = Planck length / c = 10**(-43) seconds !!!